Table 2.

Effect of total extract and primary fractions obtained from Cryptostegia grandiflora leaves on MPO activity in ear tissue

Treatment	Dose (mg/ear)	MPO activity (U/mg of tissue)	Inhibition percentage (%)
Control (TPA + acetone)	— — —	18150 ± 2012.3	—
Indomethacin	0.5	4040 ± 406.9	77.7 ± 2.2***
Cryptostegia grandiflora
Total extract	1.0	11040 ± 987.8	39.1 ± 5.4***
Ether fraction	1.0	600 ± 89.4	96.6 ± 0.4***
Dichloromethane fraction	1.0	666 ± 98.8	96.3 ± 0.5***

Results are expressed as mean ± S.M.E. (n = 6) (***p < 0.001 ANOVA, statistically significant compared with control group).