Figure 3.

HZE and gamma induce DNA metabolic transcripts 1.5 h after IR. (A) The Venn diagram shows the overlap of the 280 gamma radiation and 1169 HZE-induced transcripts at 1.5 h after irradiation (fold change >2 and adjusted p-value < 0.05). We used the 1.5 h unirradiated control for the 1.5–12 h time points and the 24 h unirradiated control for the 24 h time point. (B) The bar graph shows the fold enrichment of the gamma radiation unique, HZE unique, and shared induced transcript sets shown in the Venn diagram in (A) for each GO category that is significantly overrepresented in at least one of these transcript sets.