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. Author manuscript; available in PMC: 2015 Apr 14.
Published in final edited form as: Ann Neurol. 2014 Apr 14;75(4):563–573. doi: 10.1002/ana.24135

Figure 2. The APOE4 carrier status increases the risk of clinical decline in women with MCI more than in men.

Figure 2

The main figure shows the survival function plot for conversions from MCI to possible/probable AD based on left-truncated and right-censored data. In contrast to the Cox regression no stratification or covariate adjustment was applied. Subjects younger than 55 years were excluded (N=71; 2.7%) from the plot for visualization purposes only; the Cox model featured all available subjects. The inset depicts the hazards ratio for converting from MCI to AD computed separately for each sex using a Cox regression model (*** signifies a significant effect with P<0.001). Blue and red refer to males and females, respectively.