Fig. 2.

Viable pneumococci in lungs and blood of infected properdin-deficient and wildtype mice. a Wildtype mice limited bacterial numbers in lungs at 48 h compared to 24 h, while the numbers of viable bacteria were increased in properdin-deficient mice for these timepoints (n = 2 for t0, 5–6 for t6 h, 4–5 for t24 h, 8–10 for t48 h; ±SEM). b Properdin-deficient mice have greater bacteremia than wildtype mice at 48 h (n = 10 each group, ±SEM)