Table 1.

Serum IgM and C4c levels in sera of properdin-deficient and wildtype mice (uninfected and infected with S. pneumoniae)

	T 0	T 24H	T 48H
Serum IgM levels (ng/μl) ± SD, *p < 0.05 (compared to 0H)
Wildtype	88.1 ± 42.4 (N = 9)	42.2 ± 28* (N = 5)	46.4 ± 4.2* (N = 4)
Properdin-deficient	84.1 ± 47.9 (N = 10)	45 ± 18.9* (N = 5)	52.8 ± 8.1* (N = 5)
Serum C4c levels (semiquantitative, OD 405 ± SD), *p < 0.05 (compared to 0H)
Wildtype	1.6 ± 0.2 (N = 3)	1.9 ± 0.5 (N = 5)	2.4 ± 0.2* (N = 4)
Properdin-deficient	1.5 ± 0.1 (N = 2)	1.5 ± 0.6 (N = 5)	1.8 ± 0.4 (N = 5)