TABLE 2.
Structural homologues of MtbGpgP
Dali analysis retrieved >200 hits with a Z score above 6. Surprisingly, sequence conservation amongst the homologues is low. The top 10 hits are listed in the table.
| No. | Protein Data Bank Chain | Z-score | RMSD | Identity | Name of protein |
|---|---|---|---|---|---|
| % | |||||
| 1 | 4IJ6-B | 26.9 | 1.7 | 29 | Phosphoserine phosphatase of H. thermophilus |
| 2 | 1EBB-A | 24.5 | 2.1 | 31 | Phosphatase PhoE of B. stearothermophilus |
| 3 | 3GP3-A | 22.4 | 2.2 | 26 | Phosphoglycerate mutase of B. pseudomallei |
| 4 | 3D8H-B | 22.3 | 2.3 | 23 | Phosphatase of P. falciparum |
| 5 | 1FZT-A | 22.1 | 2.4 | 24 | Phosphoglycerate mutase of S. pombe |
| 6 | 2A9J-A | 22.0 | 2.2 | 24 | Bisphosphoglycerate mutase of Homo sapiens |
| 7 | 1RII-D | 22.0 | 2.3 | 29 | Phosphoglycerate mutase of M. tuberculosis |
| 8 | 3KKK-C | 22.0 | 2.4 | 24 | Phosphoglycerate mutase of P. falciparum |
| 9 | 3DCY-A | 21.9 | 2.6 | 27 | TP53-induced regulator of H. sapiens |
| 10 | 4EMB-A | 21.8 | 2.4 | 26 | Phosphoglycerate mutase of B. burgdorferi |