TABLE 1.

EGCG/αSN molar ratios needed for 50% inhibition of oligomer membrane permeabilization and cytotoxicity

Assays	MI50%, EGCG/oligomer (EGCG/monomer)a
Calcein release	∼7 (±2):1 (0.23:1)
OLN-93 toxicity	∼11 (±2):1 (0.36:1)

^a Molar ratio of EGCG was needed for 50% inhibition of calcein release and for 50% reduction in the decrease in cell viability caused by oligomer (i.e. from 15 to 7.5%). Ratios are given in units of oligomer concentration (monomer equivalents in parentheses based on 30 monomers/oligomer). Data were from fits to Fig. 1, A and C.