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. 2014 Jun 14;289(31):21473–21489. doi: 10.1074/jbc.M114.581702

FIGURE 7.

FIGURE 7.

Interaction of mercaptosuccinate with GPx peptides. A, mass spectra of the reaction of a Sec-containing peptide (control, top spectrum) with mercaptosuccinate (middle spectrum), and mercaptosuccinate followed by the reductant DTT (bottom spectrum). B, mass spectrum of the reaction of the Sec- and Lys-containing peptide (control, top spectrum) and with mercaptosuccinate (middle spectrum) and mercaptosuccinate followed by the reductant DTT (bottom spectrum). C, scheme demonstrating the proposed reaction between thiol-containing Tio or mercaptosuccinate and GPx.