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Conformational studies on hPg in the presence of VEK-peptides as determined by small angle x-ray scattering. A, hPg is fully open in the presence of a stoichiometric equivalent of VEK75. Plasminogen glycoform 2 was used for the experiments. B, the efficiency of VEK75 and VEK35 to induce conformational change in hPg is much higher than Lys analogues EACA and TxA.
