Table 1.
Centre number | Centre | Short name | Sample number (case/control) | Age (mean) | Gender (male per case/control group) | Urinary albumin median (range) (mg/L) case | Urinary albumin median (range) (mg/L) control | eGFR median (range) (mL/min/1.73 m2) case | eGFR median (range) (mL/min/1.73 m2) control | Area under the curve (AUC, 95% CI) |
---|---|---|---|---|---|---|---|---|---|---|
1 | Charite-Berlin | CHA | 9/9 | 57/61 | 4/1 | 368 (11–8620) | 11 (11–11) | 72 (34–104) | 87 (60–117) | 1.00 (0.815–1.000) |
2 | Faculty University of Skopje | SKO | 10/5 | 64/64 | 5/0 | 100 (0–100) | 20 (0–20) | 28 (10–48) | 85 (83–111) | 1.00 (0.782–1.000) |
3 | Hospital St Georg Leipzig | STG | 12/7 | 62/54 | 7/4 | 538 (97–1633) | 4 (0–20) | 21 (7–50) | 87 (63–111) | 0.95 (0.747–0.999) |
4 | Charles University | CUP | 10/10 | n.a. | n.a | 2043 (750–9500)a | 6 (1–16)a | 38 (19–61) | 88 (62–160) | 1.00 (0.832–1.000) |
5 | Diabetes Centre Prague | DCP | 10/10 | 63/60 | 5/6 | 2115 (450–7780)b | 8 (3–23)a | 60 (22–110) | 88 (60–131) | 0.89 (0.670–0.984) |
6 | Mario Negri Institute | MAR | 9/10 | n.a. | n.a. | 513 (217–2169)c | 5 (3–8)c | 38 (13–102) | 98 (89–128) | 0.96 (0.752–0.999) |
7 | Steno Diabetes Center | STE | 9/10 | n.a | n.a. | 346 (3–1673)c | 5 82–23)c | 42 (18–87) | 87 (68–90) | 0.98 (0.786–1.000) |
8 | IIS-Fundación Jimenez Diaz | FJD-UTE | 14/9 | 64/64 | 11/5 | 281 (2–2266)c | 4 (0–14)c | 43 (16–102) | 71 (65–105) | 0.90 (0.698–0.984) |
9 | Health Plus Abu Dhabi | Abu Dhabi | 4/8 | 67/44 * | 3/5 | 1517 (889–9895) | 15 (1–29) | 79 (19–123) | 99 (72–139) | 1.00 (0.74–1.00) |
Given are the different centres with the number of collected samples and sample characteristics. In addition, the resulted AUC (area under the curve) values obtained using the CKD273 classification score for each centre are listed.
n.a., not available.
*P < 0.05 (for age the Mann–Whitney test, for gender Fisher's exact test was used).
aAlbuminuria (mg/24 h).
bProteinuria (mg/24 h).
cAlbumin/creatinine ratio (mg/g).