Figure 4. Microbiota transfer to adult antibiotic-treated mice changes their metabolic parameters.

(a) Weekly body weight (gram) of recipient mice after inoculation with either BALB/c (female n = 8, male n = 8) or B6.-Lep^ob (female n = 8, male n = 8) at eight weeks of age. (b) Area under the curve calculated from weight data in A. (c) AUC of weekly food consumption (gram) per cage in six weeks from inoculation in recipient mice inoculated with either BALB/c (males n = 2; females n = 2) or B6.-Lep^ob microbiota (males n = 2; females n = 2) at eight weeks of age. (d) HbA1c (glycated haemoglobin, %) concentration in the blood of recipient mice six weeks after inoculation with either BALB/c (n = 16) or B6.-Lep^ob (n = 16) at eight weeks of age. (e) Oral glucose tolerance test (OGTT) six weeks after inoculation with either BALB/c (n = 16) or B6.-Lep^ob (n = 16) at eight weeks of age. Tail blood glucose relative to baseline value (−15 min) is shown at given time points after oral gavage of glucose. Mean ± SEM is shown. * represents P < 0.05; ** represent P < 0.01.