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. 2013 Sep 24;17(9):1099–1108. doi: 10.1111/jcmm.12134

Fig. 6.

Fig. 6

(A) PDGFRα/CD34 double labelling; (BE) CD34/c-kit double labelling. All the PDGFRα-positive cells (A, large intestine) in the submucosa, at the submucosal border of the circular muscle layer and in the muscle wall are also CD34-positive. (B; large intestine and C; stomach): Interstitial cells of Cajal (ICC) at the submucosal border of the circular muscle layer (ICC-SM). (D; large intestine): Intramuscular ICC (ICC-IM). (E; small intestine): ICC at the deep muscular plexus (ICC-DMP). All the ICC are c-kit-positive and CD34-negative. At the submucosal border of the circular muscle layer, the CD34-positive cells (telocytes) are located close to the submucosa while the ICC-SM are closer to the circular smooth muscle cells (B and C). Several ICC-IM are intermingled with telocytes (D). The ICC-DMP appear to be not accompanied by telocytes (E). CM: circular muscle layer; SM: submucosa. Scale bars are indicated in each panel.