Table 1.
Expression levels of 56 miRNAs were up-regulated (twofold) in 14W versus ED16 and in 4W versus ED16 lenses
| Group | ED16 | 4W | 14W |
|---|---|---|---|
| miRNA | Normalized ratio | Normalized ratio | Normalized ratio |
| rno-miR-374 | 1 | 11.913 | 15.304 |
| rno-miR-148b-3p | 1 | 4.860 | 5.722 |
| rno-miR-27a | 1 | 6.103 | 7.497 |
| rno-miR-210 | 1 | 8.017 | 10.150 |
| rno-miR-31 | 1 | 57.292 | 90.646 |
| rno-let-7i | 1 | 8.418 | 9.932 |
| rno-miR-181a | 1 | 2.527 | 2.7451 |
| rno-miR-30e | 1 | 3.2337 | 3.599 |
| rno-let-7e | 1 | 3.537 | 3.801 |
| rno-miR-128 | 1 | 4.560 | 5.939 |
| rno-miR-652 | 1 | 2.602 | 3.077 |
| Tio-niiR-181c | 1 | 2.397 | 2.788 |
| rno-let-7f | 1 | 13.347 | 22.336 |
| mo-miR-872 | 1 | 9.729 | 12.997 |
| rno-miR-30a | 1 | 6.033 | 7.850 |
| rno-let-7d | 1 | 16.821 | 25.418 |
| rno-miR-125a-5p | 1 | 2.106 | 2.339 |
| rno-miR-29b | 1 | 16.649 | 51.422 |
| rno-miR-101b | 1 | 4.976 | 9.279 |
| rno-miR-29c | 1 | 13.614 | 37.460 |
| rno-let-7b | 1 | 39.675 | 121.754 |
| rno-miR-125b-5p | 1 | 7.7633 | 14.711 |
| rno-miR-184 | 1 | 6.488 | 11.696 |
| rno-miR-204 | 1 | 5.999 | 10.187 |
| rno-miR-130a | 1 | 2.660 | 3.657 |
| rno-miR-23b | 1 | 6.940 | 13.240 |
| rno-miR-140* | 1 | 4.151 | 6.664 |
| rno-miR-101a | 1 | 7.002 | 13.307 |
| rno-let-7c | 1 | 31.570 | 82.739 |
| rno-miR-24 | 1 | 5.7109 | 9.288 |
| rno-miR-27b | 1 | 5.107 | 8.084 |
| rno-miR-384-5p | 1 | 2.008 | 2.433 |
| rno-miR-186 | 1 | 2.114 | 2.571 |
| rno-miR-425 | 1 | 10.287 | 18.866 |
| rno-let-7a | 1 | 10.6657 | 19.893 |
| rno-miR-26a | 1 | 5.751 | 9.208 |
| rno-miR-26b | 1 | 5.258 | 7.720 |
| rno-miR-99a | 1 | 8.3438 | 13.599 |
| rno-miR-338 | 1 | 14.7728 | 27.0430 |
| rno-miR-22 | 1 | 9.178 | 15.166 |
| rno-miR-100 | 1 | 18.881 | 35.391 |
| rno-miR-361 | 1 | 12.971 | 24.674 |
| rno-miR-30b-5p | 1 | 3.723 | 5.17405 |
| rno-miR-23a | 1 | 7.652 | 12.554 |
| rno-miR-221 | 1 | 2.943 | 3.799 |
| rno-miR-30c | 1 | 4.567 | 6.570 |
| rno-miR-125a-3p | 1 | 3.077 | 7.574 |
| rno-miR-29C* | 1 | 2.1587 | 3.648 |
| rno-miR-151 | 1 | 2.761 | 4.711 |
| rno-miR-211 | 1 | 2.5078 | 4.324 |
| rno-miR-487b | 1 | 2.651 | 6.823 |
| rno-miR-218 | 1 | 5.054 | 4.788 |
| rno-miR-333 | 1 | 4.005 | 3.780 |
| rno-miR-96 | 1 | 60.873 | 24.561 |
| rno-miR-182 | 1 | 7.133 | 2.129 |
| rno-miR-124 | 1 | 4.281 | 2.424 |
Up-regulation of a set of 56 miRNAs was observed in 4W and 14W lenses relative to ED16. These were derived following statistical analysis as stated in Materials and methods. The table was sorted by amount of change in 4W and 14W if ED16 normalized value is 1. miRNAs showing more than twofold relative expression were incorporated in the table.