Table 1. Mutations (including Missense point mutations/deletion/insertion) frequencies in 45 genes (737 loci) in female and male GISTs. The p-value of Fisher exact test result of KIT mutations in female and male is 0.429.

Genes	Number of samples with mutations (Mutation frequency in 121 samples)	Number of female samples with mutations (Mutation frequency in 59 female samples)	Number of male samples with mutations (Mutation frequency in 62 male samples)
ABL1	0(0.0%)	0(0.0%)	0(0.0%)
AKT1	0(0.0%)	0(0.0%)	0(0.0%)
ALK	0(0.0%)	0(0.0%)	0(0.0%)
APC	0(0.0%)	0(0.0%)	0(0.0%)
ATM	0(0.0%)	0(0.0%)	0(0.0%)
BRAF	1(0.8%)	0(0.0%)	1(1.6%)
CDH1	1(0.8%)	0(0.0%)	1(1.6%)
CDKN2A	0(0.0%)	0(0.0%)	0(0.0%)
CSF1R	0(0.0%)	0(0.0%)	0(0.0%)
CTNNB1	0(0.0%)	0(0.0%)	0(0.0%)
EGFR	1(0.8%)	1(1.7%)	0(0.0%)
ERBB2	0(0.0%)	0(0.0%)	0(0.0%)
ERBB4	1(0.8%)	1(1.7%)	0(0.0%)
FBXW7	0(0.0%)	0(0.0%)	0(0.0%)
FGFR1	0(0.0%)	0(0.0%)	0(0.0%)
FGFR2	0(0.0%)	0(0.0%)	0(0.0%)
FGFR3	0(0.0%)	0(0.0%)	0(0.0%)
FLT3	3(2.5%)	2(3.4%)	1(1.6%)
GNAS	0(0.0%)	0(0.0%)	0(0.0%)
HNF1A	0(0.0%)	0(0.0%)	0(0.0%)
HRAS	0(0.0%)	0(0.0%)	0(0.0%)
IDH1	0(0.0%)	0(0.0%)	0(0.0%)
JAK3	0(0.0%)	0(0.0%)	0(0.0%)
KDR	0(0.0%)	0(0.0%)	0(0.0%)
KIT	60(49.6%)	25(42.4%)	35(56.5%)
KRAS	1(0.8%)	1(1.7%)	0(0.0%)
MET	0(0.0%)	0(0.0%)	0(0.0%)
MLH1	0(0.0%)	0(0.0%)	0(0.0%)
MPL	0(0.0%)	0(0.0%)	0(0.0%)
NOTCH1	0(0.0%)	0(0.0%)	0(0.0%)
NPM1	0(0.0%)	0(0.0%)	0(0.0%)
NRAS	0(0.0%)	0(0.0%)	0(0.0%)
PDGFRA	1(0.8%)	1(1.7%)	0(0.0%)
PIK3CA	0(0.0%)	0(0.0%)	0(0.0%)
PTEN	1(0.8%)	1(1.7%)	0(0.0%)
PTPN11	0(0.0%)	0(0.0%)	0(0.0%)
RB1	0(0.0%)	0(0.0%)	0(0.0%)
RET	0(0.0%)	0(0.0%)	0(0.0%)
SMAD4	0(0.0%)	0(0.0%)	0(0.0%)
SMARCB1	0(0.0%)	0(0.0%)	0(0.0%)
SMO	0(0.0%)	0(0.0%)	0(0.0%)
SRC	0(0.0%)	0(0.0%)	0(0.0%)
STK11	0(0.0%)	0(0.0%)	0(0.0%)
TP53	1(0.8%)	0(0.0%)	1(1.6%)
VHL	1(0.8%)	0(0.0%)	1(1.6%)