Table 1.
Haemodynamics, cardiac geometry and function at baseline and 4 weeks after myocardial infarction
| Parameter | Baseline | 4 weeks after MI | P-value between groups | |||||
|---|---|---|---|---|---|---|---|---|
| IC | TE | Surgical | IC | TE | Surgical | Baseline | Termination | |
| n = 7 | n = 7 | n = 7 | n = 7 | n = 7 | n = 6 | |||
| HR (beats/min.) | 53 ± 4 | 55 ± 3 | 52 ± 2 | 62 ± 3 | 63 ± 2 | 57 ± 4 | 0.864 | 0.456 |
| MAP (mmHg) | 100 ± 3 | 107 ± 4 | 100 ± 4 | 89 ± 7 | 99 ± 5 | 91 ± 6 | 0.308 | 0.455 |
| LVIDED(cm) | 4.8 ± 0.2 | 4.5 ± 0.2 | 4.6 ± 0.2 | 4.8 ± 0.2 | 4.8 ± 0.2 | 4.8 ± 0.2 | 0.400 | 0.943 |
| LVIDES(cm) | 3.3 ± 0.1 | 3.1 ± 0.2 | 3.5 ± 0.1 | 3.6 ± 0.1 | 3.7 ± 0.2 | 3.9 ± 0.3 | 0.144 | 0.541 |
| FAS (%) | 49 ± 1 | 50 ± 2 | 47 ± 1 | 41 ± 2 | 36 ± 3 | 32 ± 3 | 0.333 | 0.107 |
| PV-loop derived | ||||||||
| ESP (mmHg) | 108 ± 6 | 103 ± 8 | 100 ± 6 | 95 ± 10 | 87 ± 8 | 76 ± 3 | 0.721 | 0.270 |
| EDP (mmHg) | 9.0 ± 0.5 | 8.0 ± 0.2 | 8.1 ± 0.3 | 13 ± 0.7 | 15 ± 0.7 | 15 ± 1.0 | 0.293 | 0.231 |
| dP/dtMAX (mmHg/sec.) | 1242 ± 34 | 1329 ± 86 | 1293 ± 54 | 1056 ± 128 | 1004 ± 87 | 843 ± 53 | 0.610 | 0.323 |
| dP/dtMIN (mmHg/sec.) | −1074 ± 120 | −933 ± 116 | −948 ± 84 | −960 ± 102 | −949 ± 79 | −833 ± 27 | 0.711 | 0.493 |
| EDV (ml) | 106 ± 3 | 99 ± 6 | 104 ± 5 | 131 ± 7 | 138 ± 13 | 147 ± 5 | 0.528 | 0.530 |
| ESV (ml) | 41 ± 3 | 45 ± 7 | 39 ± 3 | 62 ± 4 | 66 ± 7 | 69 ± 4 | 0.602 | 0.655 |
| EF (%) | 59 ± 3 | 61 ± 4 | 64 ± 3 | 52 ± 4 | 49 ± 6 | 52 ± 3 | 0.486 | 0.868 |
HR: heart rate; MAP: mean aortic pressure; LVIDED: left ventricular internal diameter end-diastolic; LVIDES: left ventricular internal diameter end-systolic; FAS: fractional area shortening; ESP: end-systolic pressure; EDP: end-diastolic pressure; dP/dtMAX: maximal rate of LV pressure increase; dP/dtMIN: maximal rate of LV pressure decrease; EDV: end-diastolic volume; ESV: end-systolic volume; EF: ejection fraction derived from dP/dt; PV-loop: pressure volume loop. Data are presented as mean ± SE.