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. 2014 Jul 2;14:286. doi: 10.1186/1472-6963-14-286

Table 2.

MS charges a in 2011

  N % of Total Mean [SD] charge per patient ($) P Value
All patients
15,902
100.0
26,520 [38,478]
 
By patient characteristics
 
 
 
 
Gender
 
 
 
<0.001b
 Female
12,100
76.1
26,224 [38,716]
 
 Male
3,801
23.9
27,445 [37,691]
 
 Unknown
1
0.0
90,704 [NA]
 
Age in years
 
 
 
<0.001
 17 or younger
126
0.8
14,142 [40,310]
 
 18 to 25
405
2.6
25,731 [44,296]
 
 26 to 35
2,009
12.6
26,324 [36,224]
 
 36 to 45
4,021
25.3
27,430 [36,866]
 
 46 to 55
5,030
31.6
27,558 [39,653]
 
 56 to 64
3,499
22.0
25,876 [38,022]
 
 65 or older
812
5.1
21,167 [42,005]
 
Region
 
 
 
 
 Northeast
1,861
11.7
27,035 [38,558]
0.646
 Midwest
4,480
28.2
25,820 [32,754]
 
 South
6,730
42.3
26,604 [40,196]
 
 West
2,827
17.8
27,093 [42,457]
 
 Other
4
0.0
23,745 [28,601]
 
Insurance product
 
 
 
0.032
 EPO
2,088
13.1
27,933 [42,360]
 
 HMO
1,474
9.3
24,628 [33,046]
 
 Indemnity
329
2.1
22,127 [39,181]
 
 POS
11,336
71.3
26,648 [38,173]
 
 PPO
641
4.0
26,622 [41,918]
 
 Other
34
0.2
19,353 [28,310]
 
Charge components
Utilization c Mean [SD]
Mean [SD] Cost ($)
% of Total Cost
 Inpatientd
0.48 [2.75]
3,179 [17,860]
12.0
 Outpatientd
6.05 [8.04]
9,355 [24,523]
35.3
 Emergency Roomd
0.03 [0.39]
33 [522]
0.1
 DMD 3.17 [4.87] 13,953 [21,704] 52.6

aSum of the charges for (1) medical claims with an MS diagnosis (ICD-9-CM = 340.xx in any diagnosis field or a DRG code for MS and cerebellar ataxia [DRG = 058, 059, or 060]) plus (2) medical or pharmacy claims indicating a DMD (Table 1).

bExcluding the patient with unknown gender (i.e., t-test for female versus male).

cNumber of claims. Claims counts for DMDs include both medical and pharmacy claims.

dCharges for medical claims with an MS diagnosis (ICD-9-CM = 340.xx in any diagnosis field or a DRG code for MS and cerebellar ataxia [DRG = 058, 059, or 060]).

DMD = disease-modifying drug; DRG = Diagnosis-Related Group; EPO = exclusive provider organization; HMO = health maintenance organization; MS = multiple sclerosis; NA = not applicable; POS = point of service; PPO = preferred provider organization; SD = standard deviation.