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. Author manuscript; available in PMC: 2015 Jan 3.
Published in final edited form as: Semin Reprod Med. 2014 Jan 3;32(1):56–67. doi: 10.1055/s-0033-1361823

Figure 1. IA LPS induces lung maturation but interrupts normal alveolar development in preterm lambs.

Figure 1

Sheep were given IA LPS (E. coli lipopolysaccharide) and delivered 7d later at 125d gestational age (80% gestation). (A) IA LPS increased surfactant saturated phosphatidyl choline (the largest component of pulmonary surfactant) in the airways. (B) Lung morphometry revealed ~30% fewer alveoli in the IA LPS group. (*p<0.05 vs. control, Data from [39] and [40]).