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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1979 Dec;76(12):6196–6200. doi: 10.1073/pnas.76.12.6196

Arrangement of coding and intervening sequences of chicken lysozyme gene.

W Lindenmaier, M C Nguyen-Huu, R Lurz, M Stratmann, N Blin, T Wurtz, H J Hauser, A E Sippel, G Schütz
PMCID: PMC411830  PMID: 293713

Abstract

Hybrid phages that contain chicken lysozyme gene sequences have been isolated from a chicken DNA library. Two overlapping clones covering a region of 22 kilobase pairs around this gene have been studied by restriction mapping. Southern hybridization, and electron microscopic analysis of hybrids between lysozyme mRNA and the cloned cellular DNA. Three intervening sequences interrupt the lysozyme structural gene. The cellular gene is at least 3.9 kilobases long, about 6 times the length of the structural gene.

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Selected References

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