. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Circ Cardiovasc Imaging. 2014 May;7(3):552–562. doi: 10.1161/CIRCIMAGING.113.001396

Table 2. Typical cardiac magnetic resonance (CMR) imaging features of cardiac amyloidosis.

Parameters	Comments

Characteristic morphological features of cardiac amyloidosis/restrictive cardiomyopathy as listed in Table 1	Better resolution images than echocardiography
	No limitation of difficult echo windows

Left ventricular LGE	Diffuse and subendocardial LGE of the LV myocardium is more common than patchy focal delayed enhancement
Left ventricular LGE	May be an early feature of cardiac involvement compared to increased wall thickness

Atrial LGE and function	A characteristic feature of cardiac amyloidosis
Atrial LGE and function	Atrial function can be studied well with CMR

T1 mapping	Subendocardial T1 relaxation time may be shortened in cardiac amyloidosis
T1 mapping	This is an early feature of cardiac amyloid involvement

Extracellular volume estimation based on T1 mapping and hematocrit measures	Extracellular volume expansion may permit an early diagnosis of cardiac amyloid even before overt left ventricular LGE

LGE = late gadolinium enhancement