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. 2014 Jul 9;15:81. doi: 10.1186/1471-2156-15-81

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Copyright © 2014 Scharpf et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Low-level data and posterior summaries from a Bayesian finite mixture model supporting copy number alterations. (A) A histogram of the average log R ratios at CNP-10Mb (gray). The posterior distribution approximated by the Gibbs sampler is indicated by the black lines overlaying the histogram. (B) The average log R ratios at the CNP-9Mb and CNP-10Mb chromosome 4 loci. (C) Same as (A) for the CNP-9Mb locus. (D) The log-transformed intensities for alleles A and B allele at a SNP in the CNP-10Mb locus. The genotype clusters are consistent with the copy number estimates from the mixture model.