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. 2014 Jul 9;15:81. doi: 10.1186/1471-2156-15-81

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Copyright © 2014 Scharpf et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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SNP and CNP associations near SLC2A9 with and without adjustment for genome-wide significant SNP rs7675964. Top: Negative log10p-values derived from a likelihood ratio test comparing a null model with clinical and technical covariates to an extended model evaluating the marginal association of SNPs (gray circles) or CNP×gender (black rectangles). The region shaded in light gray is the location of the SLC2A9 gene. Bottom: Negative log10p-values from a likelihood ratio test comparing an extended model with SNPs or CNP × gender to a null model that includes the rs7675964 genotypes.