3D- HPLC-DAD fingerprint of the ASHMI extract. Peak analysis and assignment were performed using standard samples and/or LC-MS method. Matrine, sophocarpine, oxymatrine, kushenol O, trifolirhizin correspond to the compounds from Radix Sophorae Flavescentuis. Ganoderic acid B, D, A, H, and F and ganolucidic acid D correspond to Ganoderma lucidum; Liquiritin, liquiritigenin, 7, 4'dihydroxyflavone, Isoononin, 3’7-Dihydroxy-4’-methoxy-isoflavone, and glycyrrhizic acid correspond to compounds from Radix glycyrrhiza. D- HPLC-DAD, 3 dimensional high high-performance liquid chromatography with diode array detection; LC-MS, Liquid chromatography -Mass Spectroscop(116)