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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Sci Transl Med. 2014 Feb 5;6(222):222ra16. doi: 10.1126/scitranslmed.3007988

Figure 4. Inferred transcriptional co-expression profiles and pathway enrichment of peritoneal macrophage secretion signature.

Figure 4

(A) Transcripts from the IRIS compendia rank-ordered according to median correlation distance to cytokines differentially secreted by isolated peritoneal macrophages (left). Inferred co-expression of macrophage surface markers and reported disease markers among the top 10% of proximal transcripts (right). (B) Conservation of highly enriched Canonical Pathway gene sets between IRIS and HICT co-expression profiles (FDR<0.01) following gene set enrichment analysis. The top eight positively enriched gene sets among the shared subset are listed.