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Histone marks and the modifying enzymes that act to “write” or “erase” these marks
| Histone modification | Histone mark(s) | “Writer” | “Eraser” |
|---|---|---|---|
| Acetylation (H3, H4) | H3K9ac, H3K14ac, H3K18ac | Gcn5, PCAF | HDAC1, HDAC2 |
| H3K14ac, H3K18ac, H4K5ac, H4K8ac | CBP, p300 | HDAC1, HDAC2 | |
| Methylation | H3K4me1 | SET7 | LSD1, JARID1B |
| H3K4me2, H3K4me3 | MLL | LSD1, JARID1A-D | |
| H3K27me2, H3K27me3 | EZH2 | JMJD3, UTX | |
| H3K9me2, H3K9me3 | G9a, SUV39H | LSDI, JMJD2A-D | |
| Phosphorylation | H3S10p | MSK1, MSK2? | unknown |
