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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Autism Open Access. 2012 Sep 5;Suppl 1:001. doi: 10.4172/2165-7890.S1-001

Figure 1. Genetic mouse models of 22q11.2 CNVs.

Figure 1

Over-expression (left) and deletion (right) cases are indicated. Vertical bars indicate the extent of chromosomal segments over-expressed or deleted. Phenotypes consistent (red) and inconsistent (black) with those associated with ASD are shown. a) hyperactivity, sensitization, social behaviors and clozapine-response are measured [85]; b) social interaction, working memory, prepulse inhibition (PPI), and anxiety and motor behavior were measured [93]; c,d,e,f and g) auditory PPI was measured. c[97], d[98], e[99], f[100], and g[94].