Figure 2. A) Active affiliative (affiliative), aggressive, and passive affiliative (pasasive) forms of social interaction inTbx1 WT and HT mice.

Time spent(mean ± SEM) in the three forms of social interaction in two 5-min sessions with an age-matched stimulus C57BL/6J mouse is shown. Asterisks indicate statistically significant differences between WT and HT mice at levels of 0.05(*) and 0.01(**), as determined by Newman-Keuls comparisons. B) Ultrasonic vocalization of pups during a 5-min separation from mothers at postnatal days 7–8. The average duration (mean±SEM) of each vocal call type is shown. Distinct catagories of calls, as defined by Scattoni and colleagues [138], are indicated as: cx, complex; ham, harmonics; ts, two syllable; u, upward; d, downward; h, hump(a.k.a., chevron); sh, shorts; c, composite; fs, frequency steps; f, flat. An asterisk indicates a statistically significant difference between WT and HT mice at levels of 0.05(*) and 0.01 (**) as determined by Newman-Keuls comparisions. C) Spontaneous alternation in T-maze. The percentage of repeated visits to the same am (mean ± SEM) is shown. Mice were tested with 0-, 30-, and 60-s delays between trails. An asterisk indicates a statistically significant difference between WT and HT mice at 0.01 (**) at each delay (solid line), as determined by Newman-Keuls comparisions. This figure is reproduced from [101] with permission of the Oxford Press.