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PSA promotes IL-10 production by human peripheral blood mononuclear cells in vitro. Cytokine production (pg/mL) by human peripheral blood mononuclear cells after culture for 5 days with 100 U/mL recombinant IL-2 and αCD3/CD28 beads (cell-to-bead ratio 4:1) in the presence or absence of 100 μg/mL of PSA, 5 ng/mL of recombinant TGF-β, and 4 nM of RA.
