Table 3. Association of DNA hypermethylationed ABCG1, GALNT2 and HMGCR genes with clinic characteristics.

Characteristics	ABCG1				GALNT2				HMGCR
	U	M	P-value	P-value*	U	M	P-value	P-value*	U	M	P-value	P-value*
	(Mean ± s.e.)	(Mean ± s.e.)			(Mean ± s.e.)	(Mean ± s.e.)			(Mean ± s.e.)	(Mean ± s.e.)
Age(yrs)	57.28±10.01	60.44±9.05	O.O66	0.651	57.28±9.87	62.10±8.21	0.004	0.008	57.79±9.55	63.24±8.10	0.003	0.014
Gender (M/F)	25/21	63/30	0.125	0.423	48/30	40/21	0.624	0.971	62/26	36/15	0.987	0.139
Smoking(Y/N)	17/29	47/46	0.132	0.819	34/44	30/31	0.512	0.522	50/48	14/27	0.071	0.033
Hypertension(Y/N)	21/25	58/35	0.063	0.413	42/36	37/24	0.422	0.897	55/43	24/17	0.793	0.315
Diabetes(Y/N)	3/43	25/68	0.010	0.212	16/62	12/49	0.902	0.144	16/82	12/29	0.087	0.204
CHD(Y/N)	8/38	77/16	<0.001	<0.001	39/39	46/15	0.003	0.008	56/42	29/12	0.136	0.459
TC(mmol/l)	4.44±0.99	4.50±1.18	0.735	0.285	4.41±1.20	4.57±0.99	0.401	0.625	4.46±1.16	4.53±1.02	0.762	0.082
TG(mmol/l)	1.60±0.76	1.89±2.73	0.525	0.513	1.86±2.97	1.70±0.78	0.680	0.943	1.82±2.66	1.73±0.84	0.845	0.243
HDL-C(mmol/l)	1.10±0.369	1.10±0.27	0.900	0.252	1.10±0.31	1.10±0.29	0.919	0.861	1.12±0.30	1.05±0.30	0.205	0.071
LDL-C(mmol/l)	2.64±0.77	2.73±1.01	0.615	0.166	2.61±0.97	2.81±0.88	0.198	0.325	2.69±0.94	2.72±0.93	0.863	0.117

M: methylationed; U: unmethylationed; P-value*: adjusted for age, gender, smoking (smoker vs never smoker), lipid level, history of hypertension, and history of diabetes by Cox regression. P<0.05 is considered statistically significant.