Table 2. Summary table of studies reporting carriage of Haemophilus influenzae.
Reference | Study period | Country | Sample size | Prevalence | Age group | Prevalence of carriage, % (95% CI) | |
Low income countries | |||||||
Healthy population | |||||||
[43] | Kwambana et al. 2011 | NR | The Gambia | 30 infants | Average | 0–12 months | 70 (65–74) |
[72] | Adegbola et al. 1998 | NR | The Gambia | 3986 children | Point | 1–2 years | Urban: 5.6a Rural: 10.9 |
[55] | Abdullahi et al. 2008 | 2004b | Kenya | 450 individuals | Point | 0–4 years | 26.0 |
5–9 years | 24.0 (16–33) | ||||||
10–85 years | 3.0 | ||||||
[74] | Williams et al. 2011 | 2007 | Nepal | 2195 children | Point | 0–13 years | 5.0 (3.9–6.4) |
Immunocompromised population | |||||||
No data found | |||||||
Sick population | |||||||
No data found | |||||||
Lower-middle income countries | |||||||
Healthy population | |||||||
[75] | Das et al. 2002 | 2000–2001 | India | 566 children | Point | 5–12 years | 28.6 |
[76] | Sekhar et al. 2009 | 2005–2006 | India | 1000 children | Point | <2 years | 11.2 |
[73] | Gessner et al. 1998 | NR | Indonesia | 484 children | Point | 0–24 months | 4.6 (3.7–5.5)c |
[36] | Vu et al. 2011 | 2007–2008 | Vietnam | 350 children | Point | <5 years | 31.4 |
Immunocompromised population | |||||||
[70] | Bhattacharya et al. 2012 | 2008–2009 | India | 148 children with HIV | Point | 1–16 years | 24 |
[71] | Mwenya et al. 2010 | 2002–2003 | Zambia | 439 children with HIV | Point | 6 months–14 years | 29 |
Sick population | |||||||
[62] | Mastro et al. 1993 | 1989–1990 | Pakistan | 601 children with ARI | Point | Mean:14.5 months | 36.6 |
[61] | Lupisan et al. 2000 | 1994 | The Philippines | 956 children with severe pneumonia, suspected meningitis, or clinical suspicion of sepsis | Point | 0–59 months | 15.2 |
[36] | Vu et al. 2011 | 2007–2008 | Vietnam | 274 children with radiologically confirmed pneumonia | Point | <5 years | 50 |
276 children with other LRTI | 53.5 |
ARI, acute respiratory infection; HIV, human immunodeficiency virus; LRTI, lower respiratory tract infection; NR, not reported.
All carriage rates are from the control group.
Post-vaccination data.
Age- and population-weighted carriage rate, adjusted for design effect.