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. 2014 Aug 1;9(8):e103327. doi: 10.1371/journal.pone.0103327

Figure 4. Orthotopic xenograft “AVATAR” models recapitulate the subtypes of their parental GBMs.

Figure 4

(A) Predicted molecular subtypes of 25 GBM patients from the SMC GBM dataset and corresponding orthotopic xenograft “AVATAR” models were summarized. *, matched case. PN = Proneural, NL = Neural, CL = Classical, MES = Mesenchymal, ND = not-determined. (B) Subtype classification of 25 GBM patients by the NTP methods was compared with subtypes of corresponding orthotopic xenograft “AVATAR” models.