Table 1. Demographics, sputum microbiology and antibiotic therapy of CF patients.
Patient # | Sex | Age (years) | Sputum microbiology | Antibiotic therapy | FEV1 (% predicted) | FVC (% predicted) | WBC (*1000/mm3) | PMN (% of WBC) | CRP (mg/dl) | |||||
Pre- therapy | Post-therapy | Pre- therapy | Post-therapy | Pre- therapy | Post-therapy | Pre- therapy | Post-therapy | Pre- therapy | Post-therapy | |||||
1 | M | 36 | S. aureus | Ceftazidim Tobramycin | 28.9 | 37.7 | 43.3 | 54.6 | 10.69 | 9.41 | 66 | 54.7 | 3.6 | 1.4 |
2 | M | 27 | P. aeruginosa (mucoid) A. fumigatus | Ceftazidim Tobramycin | 25.7 | 31.5 | 37.0 | 44.9 | 10.37 | 6.54 | 74.8 | 56.9 | 9.7 | 3.2 |
3 | M | 30 | P. aeruginosa S. apiospermum | Sulfametoxazole/Trimetoprim Azithromycin Tobramycin | 17.5 | 17 | 37.2 | 35.6 | 15.63 | 15.05 | 72.7 | 76.4 | 23.1 | 32 |
4 | M | 30 | N/A | Azitrhomycin Tobramycin | 35.8 | 41.6 | 52.2 | 62.5 | 6.90 | 8.08 | 55.5 | 54.2 | 3.4 | 2.8 |
5 | F | 11 | N/A | Ciprofloxacin Azithromycin | 105.7 | 99.3 | 114.6 | 107.7 | 6.43 | 4.63 | 39.9 | 37.6 | 1.4 | 1.9 |
6 | M | 16 | P. aeruginosa, S. aureus | Ciprofloxacin | 78.0 | 72.4 | 80.4 | 77.0 | 8.66 | 8.71 | 57.7 | 59.1 | 2,2 | 1.4 |
7 | M | 29 | P. aeruginosa, S. aureus, H. influenzae | Meropemen Amikacyin | 19.1 | 17.7 | 31.4 | 25.6 | 9.68 | 6.79 | 81.6 | 62.5 | 27.6 | N/A |
8 | M | 17 | P. aeruginosa | Ciprofloxacin Azithromycin | 65.4 | 95.9 | 84.7 | 104.1 | 10.20 | 8.87 | 60.1 | 58.1 | 24.0 | 3.2 |
9 | F | 29 | B. cepacia | Minociclin | 20.7 | 22.6 | 29.9 | 32.4 | 11.87 | 12.17 | 60.7 | 62.3 | 103.8 | 73.1 |
10 | M | 42 | P. aeruginosa | Ciprofloxacin Azithromycin | 17.8 | 19.8 | 33.9 | 31.1 | 8.21 | 6.94 | 60.5 | 62.8 | N/A | N/A |
11 | M | 24 | N/A | N/A | 50.4 | 67.9 | 64.9 | 78.4 | 4.37 | 8.33 | 55.6 | 70.7 | 12.1 | 2.9 |
12 | M | 19 | P. aeruginosa, S. aureus | Ciprofloxacin | 57.0 | 59.7 | 79.0 | 84.0 | 10.33 | 9.85 | 57.1 | 42.9 | 14.6 | 6.3 |
13 | F | 16 | S. aureus | Minociclin Teicoplanin | 32.1 | 34 | 40.8 | 48.3 | 7.98 | 9.56 | 45.0 | 40.5 | 13.8 | 2.5 |
14 | F | 39 | P. aeruginosa | Amikacin Meropenem Ciprofloxacin Tigecycline | 40.1 | 46.6 | 52.6 | 58.9 | 7.6 | 7.7 | 61.7 | 60.3 | 5.0 | 2.0 |
15 | M | 28 | S. aureus B. cepacia | Ceftazidim Tobramycin | 62.8 | 63.8 | N/A | 86.5 | 7.05 | 12.3 | 57.1 | 57.7 | 3.8 | 1.4 |
16 | M | 21 | P. aeruginosa | Ciprofloxacin | 92.5 | 100.0 | 107.0 | 109.0 | 10.29 | 8.23 | 64.5 | 47.4 | 4.2 | N/A |
N/A: not available.