Table 3. Up-regulated genes in blood PMN of CF patients vs. controls subjects with biological plausibility.

Biological process	Accession number	Gene coding for	p-value*	Fold change
Apoptosis	NM_000212	ITGB3 (integrin, beta 3)	0.044	2.09
Immune response	NM_000610	CD44	0.0009	1.95
Inflammation, apoptosis	NM_004895	NLRP3 (NLR family, pyrin domain containing 3)	0.011	2.33
Inflammation, signal transduction	NM_020370	GPR84 (G protein-coupled receptor 84)	0.007	2.37
Signal transduction	NM_002184	IL6ST (interleukin 6 signal transducer; gp130;oncostatin M receptor)	0.034	1.74

*from unpaired t-test.