Table 1. Demographic and clinical data of the individuals with 22q11Ds included in the study.

Individual	Age	Gender	Deletionsize	Type ofCHDa	Hypocalcemiab	Seizuresd	RenalAbnb	ThyroidAbnb	Left HPCVolume(mL)e	RightHPCVolume(mL)e	WholeBrainVolume(mL)f	HeadCircumference
1	9	F	3 Mb	0	2	0	0	0	1.63	1.88	1242.56	54.60
2	8	M	3 Mb	0	0	2	0	2	1.32	1.43	1070.68	48.5
3	15	M	3 Mb	0	0	0	0	0	1.75	1.97	1231.16	54.5
4	14	M	3 Mb	0	0	0	0	0	1.6	1.67	1353.01	59 (N/A)
5	8	M	3 Mb	0	0	0	0	0	1.67	1.75	1294.11	52
6	10	M	3 Mb	TOF, VaR	0	0	N/Ac	0	1.29	1.35	1089.06	51.75 (N/A)
7	11	F	3 Mb	TA	2	0	2	2	0.9	0.95	1006.1	49.5
8	9	M	3 Mb	VR	0	0	0	0	1.47	1.63	1243.89	53
9	11	M	3 Mb	TOF, PA	2	0	0	0	N/A	N/A	1188.26	52.07
10	15	F	3 Mb	TOF, VSD	0	0	0	0	1.09	1.27	1084.95	N/A
11	12	F	3 Mb	VR, BAV	2	0	0	0	1.56	1.5	1234.23	57
12	8	M	3 Mb	0	0	0	0	0	1.41	1.27	1237.97	53.5
13	11	M	3 Mb	0	0	0	0	0	N/A	N/A	N/A	53.5
14	14	M	3 Mb	0	2	0	0	2	1.35	1.54	1200.58	55.2
15	5	M	3 Mb	0	0	0	0	0	N/A	N/A	N/A	55.5
16	4	F	3 Mb	TA	2	1 & 2	0	2	N/A	N/A	N/A	50.5
17	4	F	3 Mb	TA	2	1	0	2	N/A	N/A	1108.88	50.5
18	11	F	3 Mb	VSD	0	0	0	0	N/A	N/A	N/A	51.5
19	11	M	3 Mb	0	2	1	0	0	N/A	N/A	1432.14	57
20	6	M	3 Mb	ASD/VSD	0	0	0	0	N/A	N/A	1214.46	51.5
21	8	M	3 Mb	VR	0	2	2	0	N/A	N/A	N/A	56
22	8	M	3 Mb	0	0	0	2	0	N/A	N/A	N/A	52.5
23	8	M	3 Mb	TOF	2	0	0	0	N/A	N/A	N/A	54.6
24	11	F	3 Mb	PDA, ASD/VSD, PFO	0	0	0	0	N/A	N/A	N/A	53.5
25	5	F	3 Mb	TOF	0	0	0	0	N/A	N/A	N/A	52.07
26	4	F	3 Mb	0	N/Ac	N/A	N/A	N/A	N/A	N/A	N/A	N/A
27	5	M	3 Mb	0	0	0	N/A	N/A	N/A	N/A	N/A	51
28	8	M	3 Mb	0	0	0	0	0	1.54	1.66	1279.48	54.6
29	3	F	3 Mb	ASD/VSD	0	0	0	0	1.21	1.61	9572.97	48.5
30	9	M	1.5 Mb	IAA, ASD/VSD, mild aortic stenosis	2	1 & 2	0	0	1.78	1.91	1206.48	53

^aTOF = Tetralogy of Fallot; PA = Pulmonary Atresia; VSD = Ventricular Septal Defect; TA = Truncus Arteriosus; VR = Vascular Ring; BAV = Bicuspid Aortic Valve, VaR = Valve Replacement; ASD = Atrial Septal Defect; AAA = Aortic Arch Abnormalities; IAA = Interrupted aortic arch.

^b0 = No; 2 = Yes.

^cN/A = Data not available.

^d0 = No; 1 = Hypocalcemic seizures; 2 = Yes.

^eAverage hippocampal volume for TD individuals is 2 mL.

^fAverage whole brain volume for TD individuals is 1200 mL.

HPC = hippocampus.

Abn = abnormality.