Table 2. Parameters at baseline.
Dobutamine (n = 14) | Enoximone (n = 10) | Norepinephrine (n = 9) | P-value | |
HR, bpm | 84 [59–99] | 91 [78–107] | 101 [84–118] | NS |
MAP, mmHg | 66 [60–71] | 68 [62–81] | 55 [51–58] | 0.006 |
CVP, mmHg | 14 [11–17] | 14 [9–16] | 16 [12–19] | NS |
PCWP, mmHg | 19 [16–25] | 23 [17–25] | 20 [17–27] | NS |
MPAP, mmHg a | 27 [21–33] | 33 [28–37] | 28 [25–39] | NS |
CI, L.min−1.m−2 | 2.2 [1.7–2.5] | 1.9 [1.7–3.2] | 2.6 [1.6–3.2] | NS |
SVR, dynes.sec.cm−5 | 1182 [743–1502] | 1057 [843–1246] | 837 [555–1031] | NS |
SvO2, % | 64 [60–68] | 62 [56–71] | 67 [61–70] | NS |
Lactate, mmol.L−1 | 1.4 [1.1–4.6] | 1.3 [1.1–2.9] | 2.1 [1.1–2.8] | NS |
Delta-T, °C | 6.6 [4.5–6.9] | 6.1 [4.3–7.5] | 6.2 [3.7–13.9] | NS |
PCD, mm.mm−2 | 9.3 [8.0–10.1] | 9.1 [8.9–10.2] | 9.8 [8.6–11.9] | NS |
Abbreviations: HR, heart rate; MAP, mean arterial pressure; CVP, central venous pressure; PCWP, pulmonary capillary wedge pressure; MPAP, mean pulmonary artery pressure; CI, cardiac index; SVR, systemic vascular resistance; SvO2, mixed-venous oxygen saturation; delta-T, central-peripheral temperature gradient; PCD, perfused capillary density.
Values represent median [interquartile range]. P-values≥0.05 (NS, non-significant) are not shown.
A pulmonary artery catheter was present in 27/33 (82%) of the measurements.