TABLE 3.

Intraclass Correlation Coefficients Between Siblings in a Study of White Matter Integrity in Bipolar Disorder^a

White Matter Tract or Region	Intraclass Correlation Coefficient	p	pFDR
Left uncinate fasciculus	0.28	0.02	0.03*
Right uncinate fasciculus	0.38	0.002	0.006**
Left cingulum bundle	0.48	0.001	0.005**
Right cingulum bundle	0.19	0.08	0.09
Left cingulum (hippocampal)	0.36	0.003	0.008**
Right cingulum (hippocampal)	0.40	0.001	0.005**
Left superior longitudinal fasciculus	0.45	0.0002	0.001**
Right superior longitudinal fasciculus	0.48	0.0004	0.001**
Left external capsule	0.27	0.02	0.03*
Right external capsule	0.31	0.01	0.02*
Left anterior limb of internal capsule	0.47	0.0002	0.001**
Right anterior limb of internal capsule	0.36	0.004	0.008**
Left posterior limb of internal capsule	0.34	0.005	0.01**
Right posterior limb of internal capsule	0.33	0.006	0.01**
Left retrolenticular internal capsule	−0.04	0.61	0.61
Right retrolenticular internal capsule	0.21	0.06	0.07
Left posterior thalamic radiation	0.23	0.05	0.06
Right posterior thalamic radiation	0.35	0.004	0.008**
Forceps major	0.22	0.06	0.06
Forceps minor	0.31	0.05	0.06
Fornix (column and body)	0.36	0.003	0.008**
Entire tract-based spatial statistics skeleton	0.37	0.003
Sibling < comparison cluster	0.44	0.0004
Patient < comparison cluster	0.40	0.001

^aFDR=false-discovery rate.

^*p_FDR<0.05.

^**p_FDR<0.01.