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Mean change in CGI-S from baseline to Week 52 by ADT group and week (efficacy sample, OC). Mean (SE) baseline CGI-S scores: bupropion plus aripiprazole, 4.2 (0.1); SSRI/SNRI plus aripiprazole, 4.2 (0.0). ADT, antidepressant treatment; CGI-S, Clinical Global Impressions–Severity score; OC, observed case; SNRI, serotonin–norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.
