Table 3.
The test substance | Experimental and reference values of log P | |||
---|---|---|---|---|
log Pexp. n-oct/buf pH=6.8 a | log P | log P pH = isoelectric point b | log Ptrue b | |
Ciprofloxacin | −0.55 | −1.10 n-oct/buf pH = 7 c | −1.07 | −0.13 |
Norfloxacin | −0.92 | −1.52 n-oct/buf pH = 7 c | −1.07 | −0.43 |
Pefloxacin | 0.19 | 0.26 n-oct/buf pH = 7 c | 0.37 | 1.34 |
Sparfloxacin | −0.11 | −0.31 d | −0.09 | 0.39 |
Gatifloxacin | −0.80 | - | −0.71 | 0.54 |