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. 2014 Jul 2;3:552. doi: 10.1038/bonekey.2014.47

Table 1. Overview of different models for glucocorticoid-induced bone loss given in the reported dose.

Strain Gender Age (weeks) Pellet dose (mg)a Doseb (mg per kg BW per d) Duration (weeks) Source
FVB/N Female 24 3.5   4 3
Intercross: Black Swiss and 129SvJ Male 32 5 2.1 4 1,4
Swiss Webster Male 24 5   0–8 5
Swiss Webster Male 28   2.1 8 2
Swiss Webster Male 24   1.4 3 6
FVB/N, 129SvJ Female 10 15 12.5 2 7
C57BL/6 Male 20 7.5   4 8

Abbreviations: BW, body weight; d, day.

aUsing 60-day slow-release pellets

bFor scaling the dose per mouse to the equivalent dose in humans, the dose per kg BW should be calculated with the weight in relation to the metabolic rate (for mice, weight in kg to the ¾ power9).