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. 2014 Jul 25;46(7):e107. doi: 10.1038/emm.2014.43

Figure 1.

Figure 1

Differential expression of microRNA-17-5p (miR-17-5p) in patients and HMSC-bm cell lines. (a) Quantitative reverse transcription-PCR analysis of the expression of mature miR-17-5p in the primary culture cells obtained from OA and non-traumatic ON patients. The expression of mature miR-17-5p is significantly higher in cells from osteonecrosis (non-traumatic ON) compared with those from hip osteoarthritis (OA) patients (P=0.0002). (b) MiR-17-5p expression in HMSC-bm cells stimulated by BMP-2. Cells were harvested at the indicated times, and the endogenous expression level of miR-17-5p was measured. Solid and white bars indicate samples treated with and without BMP-2, respectively. *P<0.05.