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. 2014 Jul 8;4(7):e409. doi: 10.1038/tp.2014.57

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Copyright © 2014 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Plasma levels (±s.e.m.) of adrenocorticotropic hormone (a, ACTH), corticosterone (b, CORT) and adrenalin (c) of serotonin transporter (5-HTT) homozygous knockout (5-HTT^−/−), heterozygous knockout (5-HTT^+/−) and wild-type (5-HTT^+/+) rats (n=5–8) exposed to daily 3 h separations (MS180) or a control treatment (MS0). The plasma CORT concentrations were found to be significantly affected by the interaction of 5-HTT genotype and early life treatment (G × E, P<0.05).