Skip to main content
. 2014 Jul 31;20:1132–1136.

Table 2. Prediction of the functional impact of missense mutations.

Mutation SIFT Polyphen-2 (HumDiv) Polyphen-2 (HumVar)
R21C
 0.01
 Probably damaging
 Probably damaging
T92I
 0.07
 Possibly damaging
 Possibly damaging
C110S
 0
 Probably damaging
 Probably damaging
G182V
 0
 Probably damaging
 Probably damaging
C187G
 0
 Probably damaging
 Probably damaging
Y178C
 0
 Probably damaging
 Probably damaging
P347L 0 Probably damaging Probably damaging