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. 2014 Jul 31;20:1075–1084.

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Copyright © 2014 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Proliferating progenitor cells express tuba1a:GFP transgene following light damage. tg:1016tuba1a:GFP zebrafish were exposed to the constant intense light paradigm, and retinas were collected at the indicated time points and assessed for green fluorescent protein (GFP, green) and proliferating cell nuclear antigen (PCNA, red) expression in the central-dorsal retina by immunohistochemistry. Small clusters of GFP⁺/PCNA⁺ cells associate with MG processes at 51 h (double arrowheads). Large clusters of GFP⁺/PCNA⁺ cells span in the INL at 72 h (arrows). Arrowheads indicate rod precursors in the ONL. ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer; IPL, inner plexiform layer. Scale bar is 50 µm.