Skip to main content
. 2014 Jul 1;107(1):126–133. doi: 10.1016/j.bpj.2014.05.018

Figure 2.

Figure 2

Chloride dependence of Boltzmann characteristics of eM and NLC as a function of depolarizing and hyperpolarizing ramps. (A) NLC Vh disparities arise as chloride levels are decreased, with effects being larger on eM, and larger disparities being observed with depolarizing ramps (B). (C) Qmax, determined from NLC fits, decreases as chloride levels are lowered. Hill coefficient (n) and K1/2 are shown. Contrarily, eM magnitude is little affected. Similar results are obtained with depolarizing ramps (D). Plots are of average (+/−se) results from combined responses to 100 ms and 500 ms ramps, (n = 5 to 15). (E) Stretched exponential changes in OHC NLC occur during a constant voltage step from + 50 mV to -110 mV. 4 μsec clock, Cm inspection resolution 0.512 ms. To see this figure in color, go online.