Figure 6.

Bifurcation analysis of the single subunit calcium model (a) Steady-state cytosolic calcium concentration (arbitrary units) as a function of agonist dose for different translocation rates (kt). The upper lines as depicted by Line of maximum indicates maximum of the oscillations. The lower lines as depicted by Lines of minimum indicates minimum of oscillations. (b) Real part of Eigen values as a function of agonist dose (for different kt) (c) Dynamic phase response in terms of cytosolic calcium concentration versus βγ subunit concentration at the plasma membrane for different values of kt. (d) Steady-state calcium concentration as a function of translocation rate constant kt for an agonist dose. The line of maximum and minimum indicates as mentioned in (a). The single subunit calcium model was simulated for various translocation rates to obtain the previous results. In (a–c), kt values used are kt = 0 (black), kt = 0.05 (red), kt = 0.1(blue), kt = 0.2 (purple). To see this figure in color, go online.