Figure 3.

Long-term NIH3T3 cell motion. (Top) Scheme describing the long-term biophysical parameters of persistence length L_p, persistence time T_p, speed v, and pausing time T_pa for the + and − directions. The lattice units are represented as l.u. (a) Time-lapse sequence for 48 h of an NIH3T3 fibroblast fluctuating on circular fibronectin patches. (b) Time-lapse sequence for 30 h of an NIH3T3 fibroblast (i) fluctuating on the ratchet and (ii) migrating directionally toward the + end. Scale bars: 100 μm. Time in hh:mm. To see this figure in color, go online.