Table 3. Skin, hair and eye colour distribution for each TYR genotype.
| TYR genotypea | TYR genotype phaseb | TYR Protein phasec | Combined Allelic Strengthd | Skin coloure | Hair colourf | Eye colourg | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N (%) | Fair % | Medium % | Olive/dark % | N (%) | Red % | Fair/ blond % | Light brown % | Dark brown % | Black % | N (%) | Blue % | Green % | Brown % | ||||
| A | 1-1/1-1 | S-R/S-R | 6 | 502 (13.4) | 33.3 | 44.8 | 21.9 | 711 (13.2) | 7.0 | 12.8 | 32.3 | 38.3 | 9.6 | 172 (9.9) | 32.6 | 31.1 | 36.2 |
| B | 1-1/2-1 | S-R/Y-R | 5 | 884 (23.7) | 40.5 | 45.1 | 14.4 | 1222 (22.6) | 7.4 | 16.8 | 33.2 | 38.2 | 4.3 | 350 (20.1) | 38.3 | 33.7 | 27.9 |
| C | 1-1/1-2 | S-R/S-Q | 4 | 759 (20.4) | 43.2 | 44.8 | 12.0 | 1123 (20.8) | 7.2 | 14.3 | 33.9 | 39.6 | 4.9 | 374 (21.5) | 46.9 | 30.3 | 22.8 |
| E | 2-1/2-1 | Y-R/Y-R | 4 | 410 (11.0) | 40.5 | 49.0 | 10.5 | 602 (11.2) | 6.3 | 19.1 | 36.7 | 34.9 | 3.0 | 193 (11.1) | 45.2 | 29.0 | 25.8 |
| D/F | 1-1/2-2 2-1/1-2 | S-R/Y-Q Y-R/S-Q | 3 | 776 (20.8) | 47.4 | 45.2 | 7.3 | 1126 (20.9) | 6.1 | 17.2 | 36.9 | 35.2 | 4.6 | 400 (22.9) | 49.6 | 26.9 | 23.4 |
| G | 2-1/2-2 | Y-R/Y-Q | 2 | 46 (1.2) | 52.2 | 45.7 | 2.2 | 57 (1.1) | 8.8 | 12.3 | 45.6 | 28.1 | 5.3 | 31 (17.8) | 67.4 | 15.2 | 17.4 |
| H | 1-2/1-2 | S-Q/S-Q | 2 | 305 (8.2) | 54.8 | 40.0 | 5.2 | 482 (8.9) | 6.2 | 22.0 | 35.1 | 33.0 | 3.7 | 190 (10.9) | 60.9 | 20.8 | 18.3 |
| I | 1-2/2-2 | S-Q/Y-Q | 1 | 42 (0.02) | 69.0 | 26.2 | 4.8 | 68 (1.3) | 7.4 | 29.4 | 39.7 | 22.1 | 1.5 | 32 (1.8) | 71.1 | 15.6 | 13.3 |
| J | 2-2/2-2 | Y-Q/Y-Q | 0 | 1 (0.0) | 100 | 0.0 | 0.0 | 2 (0.004) | 0.0 | 100 | 0.0 | 0.0 | 0.0 | 1 (0.057) | 100 | 0 | 0 |
a, b
Genotypes designated in Table S3 for rs1042602*C/A and rs1 126809*G/A
c
Protein phases designated at S192Y-R402Q as 192S = 1, 192Y = 2; 402R = 1, 402Q = 2
d
Based on a four point scale S-R = 3, Y-R =2, S-Q =1, Y-Q = 0
e
Sample set of 3725 for skin colour,
f
Sample set of 5393 for hair colour,
g
Sample set of 1743 for eye colour in BTNS and/or melanoma study samples in which genotype phase has been determined