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. 2014 Apr 11;23(17):4597–4611. doi: 10.1093/hmg/ddu173

Figure 7.

Figure 7.

Association of SNPs in the TGFBI gene and its vicinity with T1D and T2D-related phenotype in WTCCC and MAGIC GWAS studies. (A) Significant association of 3 SNPs in the TGFBI gene and its 3′ untranslated region with T1D. Positions and –log (P-values) of SNPs from 50 kb upstream to 50 kb downstream of the TGFBI gene are indicated. The dotted line represents the Bonferroni-corrected P-value at 1.19 × 10−3. The names of 3 SNPs with P-values below the corrected P-value are indicated. (B) Significant association of a SNP in the 5′ untranslated region of the TGFBI gene with fasting glucose levels. Positions and –log (P-values) of SNPs from 50 kb upstream to 50 kb downstream of the TGFBI gene are indicated. The dotted line represents the Bonferroni-corrected P-value at 1.19 × 10−3 for one phenotype test. The name of SNP with P-value below the corrected P-value without (diamond) and with BMI-adjustment (dot) is shown.