Table 2.
Results of a secondary screen of monoamine agonists in the sapje zebrafish
| No. | Chemical name | Total number treated | Number of phenotypic sapje (%) | CAS # | MW (g/mol) | Drug action |
|---|---|---|---|---|---|---|
| 1 | Serotonin | 146 | 0 (0%) | 153-98-0 | 212.68 | Monoamine neurotransmitter |
| 2 | Ropinirole | 242 | 42 (16%) | 91374-20-8 | 296.84 | Monoamine agonist |
| 3 | Domperidone | 40 | 9 (22.5%) | 57808-66-9 | 425.91 | Monoamine antagonist |
| 4 | Bromocriptine | 40 | 9 (22.5%) | 22260-51-1 | 750.70 | Monoamine agonist |
| 5 | Pramipexole | 40 | 8 (20%) | 104632-26-0 | 211.33 | Monoamine agonist |
| 6 | Paroxetine | 59 | 10 (17%) | 110429-49-8 | 329.37 | Selective serotonin reuptake inhibitor |
| 7 | Venlafaxine | 78 | 19 (24%) | 99300-78-4 | 277.41 | Serotonin–norepinephrine reuptake inhibitor |