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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Am J Psychiatry. 2014 Aug 1;171(8):864–871. doi: 10.1176/appi.ajp.2014.13081132

Table 2.

Association between age of first unexpected death of a loved one and onset of major depressive episode, dysthymia, manic episode, and alcohol disorder compared with those who did not experience unexpected death of a loved one (N=27,534).

Age of first
unexpected
death experience
Major depression
(N=7,881)
Dysthymia
(N=2,051)
Manic episode
(N=1,855)
Alcohol disorder
(N=11,197)
N (total**) OR* (95% C.I.) OR* (95% C.I.) OR* (95% C.I.) OR* (95% C.I.)
Unexpected death occurrence at age compared to no lifetime unexpected death experience*: 5–9 750 3.56 (1.54–8.23) 2.84 (0.59–13.58) 1.22 (0.48–3.11) 1.81 (0.73–4.53)
10–14 1397 1.62 (1.05–2.52) 0.91 (0.35–2.34) 0.93 (0.60–1.45) 0.93 (0.77–1.13)
15–19 2,164 1.24 (0.94–1.63) 0.77 (0.41–1.46) 0.94 (0.56–1.56) 1.11 (0.86–1.44)
20–24 1,685 1.47 (1.12–1.93) 1.37 (0.72–2.59) 0.69 (0.36–1.32) 1.3 (0.90–1.88)
25–29 1,426 1.5 (1.10–2.03) 2.41 (1.17–4.94) 1.08 (0.50–2.35) 0.93 (0.60–1.44)
30–34 1,297 1.53 (1.13–2.06) 1.91 (1.04–3.51) 2.14 (1.19–3.83) 1.27 (0.86–1.87)
35–39 1,145 2.25 (1.61–3.16) 1.31 (0.59–2.91) 2.08 (1.05–4.13) 1.36 (0.90–2.05)
40–44 1033 1.43 (0.97–2.11) 1.24 (0.61–2.54) 2.65 (1.32–5.31) 1.12 (0.66–1.90)
45–49 787 4.33 (3.03–6.17) 3.78 (1.74–8.22) 2.01 (0.85–4.79) 3.01 (1.80–5.03)
50–54 620 2.94 (1.86–4.65) 4.67 (2.33–9.34) 5.71 (1.85–17.56) 2.68 (1.03–6.99)
55–59 440 5.77 (3.31–10.06) 4.07 (1.63–10.17) 1.99 (0.24–16.21) 4.94 (2.07–11.81)
60–64 313 7.45 (3.93–14.12) 6.77 (2.24–20.53) -- -- 7.89 (2.62–23.80)
65–69 201 10.66 (4.42–25.70) -- -- 4.71 (0.89–24.94) 3.14 (1.25–7.92)
70+ 324 2.47 (1.26–4.82) 2.14 (0.37–12.34) 5.66 (1.12–28.54) 3.23 (2.02–5.16)
*

There were 294 missing responses on age of first unexpected death experience

**

Each regression model includes a different denominator, as each model assesses the association between age of unexpected death and onset of the focal psychiatric disorder among those with no onset at a prior age. All individuals with onset of a psychiatric disorder prior to the age of unexpected death are also removed from the analysis. Dashed lines indicate that sample size was not sufficient to estimate a robust association.

***

Models were controlled for sex, age, race/ethnicity, income, education, marital status, number of lifetime potentially traumatic experiences, and onset of a psychiatric disorder prior to the focal disorder.