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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: J Immunol. 2014 Jul 14;193(4):1799–1811. doi: 10.4049/jimmunol.1400676

FIGURE 7. Post-challenge cellular immune responses in PBMC.

FIGURE 7

The frequency of memory CD4 (A, B, D) and CD8 (C, E) T cells in PBMC producing IFN-γ, IL-2, or TNF in response to PPD (A), Ag85A/b peptides (B, C), or ESAT-6 peptides (D, E) was measured 2 wks before (excluding ESAT-6) and 2, 4, 8, and 12 wks after M.tb challenge. Interquartile range (shaded box) and median (black line) for 8 animals per group are indicated. *p ≤ 0.05 compared to pre-challenge (A–C) or 2 wk post-challenge (D, E) within same group.